A £14.5m flood improvement scheme in Grimsby will reduce the risk of flooding to 14,000 properties, according to the Environment Agency.
The project will upgrade 2.2 miles (3.5km) of sea defences in the town's dock, with higher walls and earthworks.
The work will be funded by the government, with additional investment from local business.
Construction of the scheme is expected to start this summer and will take two years to complete.
The project is a collaboration between the Environment Agency, North East Lincolnshire Council, and the dock's owners Associated British Ports.
Mike Dugher, area coastal manager at the Environment Agency, said: "We have identified that the flood defences at Grimsby Docks would benefit from improvements.
"Thousands of homes and businesses in the town would be at significant risk of flooding should there be a failure of the defences."
The Environment Agency also announced upgrades to the sea defences at Cleethorpes North Promenade.