The family of a woman who disappeared 21 years ago said they want answers after the police re-opened her case.
Librarian Angela Bradley, who was 34 at the time, was last seen in Gloucester in January 1995. Her car was later found near Mythe Bridge, Tewkesbury.
She told her housemates she was "late" and "had to go"
Speaking for the first time since the case was re-opened, Mrs Bradley's brother, Philip Miles, said the family "really need to know what happened".
He added: "It's really now, after 21 years, not knowing is worse than knowing. It's the closure that we need one way or another."
Mr Miles said everyone assumed Mrs Bradley was "in the river and had taken her life".
He said she had been suffering from anorexia and depression at the time and "there was never any other theory put forward".
"My parents never believed it.... my mother thought she was still out there alive somewhere, but my father thought other things had happened. He didn't know what, but he didn't think she'd committed suicide."
"[They both] died wanting to know what happened to her without finding out," he added.
In January police said detectives from the National Crime Agency were helping with the case.
Speaking at the time, Insp Andy Matheson said detectives did not know if Mrs Bradley had been murdered or had taken her life, or whether she had disappeared and "reinvented" herself elsewhere.