A child has been airlifted to hospital with serious injuries after a crash between a car and a lorry.
Emergency services were called to the scene on the A30 near Whiddon Down, Devon, at about 12:20 BST on Sunday, police said.
Devon and Cornwall Police could not confirm the age of the child, who was taken by the Devon air ambulance to Derriford Hospital.
A second person was taken to hospital by ambulance, the fire service said.
Two crews were dispatched to the scene of the crash, according to Devon and Somerset Fire Service.
One person was trapped within one of the vehicles and was freed by hydraulic cutting equipment.
Two other injured people had been released before the arrival of fire crews, the service added.
A forensic investigation of the scene was ongoing, police said.
Police have asked people to avoid the area and anyone who saw what happened has been urged to contact the Devon and Cornwall force.
Highways England said the westbound carriageway of the A30 reopened at about 13:30 BST, but the eastbound carriageway remained closed.