Two women died after the car they were in hit a tree in Buckinghamshire and burst into flames.
The Renault Clio, which had six people inside, crashed on the A413 Amersham Road in Denham, Buckinghamshire, at about 0240 GMT, police said.
"The two women, in their early 20s, were pronounced dead at the scene.
"A man and three women, all in their 20s, were taken to Wexham Park Hospital for treatment to non-life threatening injuries," the spokesman said.
No further details were available but an investigation into the accident was under way, he added.