Housing blocks will be demolished after residents living on a South Kilburn estate voted for regeneration proposals.
Brent Council said 72% of residents took part in the referendum, with 84% backing its plans.
It means 17 housing blocks will be knocked down and rebuilt.
Councillor Shama Tatler said: "It is only right that local people had the final say on the future of their neighbourhood.“
All current tenants are guaranteed a home on the rebuilt estate, while leaseholders can choose to leave the estate with a market value payment for their home or stay with a share of the equity in one of the new homes.
Those living in temporary accommodation will be entitled to a secure tenancy in a new home on the estate when one becomes available the council said.
Campaigners who urged residents to vote ‘no’ in the ballot said they still believe the regeneration proposals are inadequate, calling for more council homes to be built and for the quality of new housing on the estate to be of a “high standard”.