Miners dominate the FTSE 100 fallers this morning, led by BHP Billiton down 1.3% at £16.78.
Advertising giant WPP is the biggest blue chip riser, up 1.8% at £12.46.
The wider FTSE 100, however, has trimmed gains and is now up 3.06 points at 7,614.70.
Shares in Hikma Pharmaceuticals soared by 8.6% to £17.88 on the FTSE 250 after it raised its sales forecast for the full-year.
It said it had sold more injectable opioids in the US and had a better-than-expected performance in generics for the first half of the year.
The FTSE 250 rose 0.29% to 20,568.95.