MPs will debate lowering the cervical screening age from 25 to 18 following a campaign by Devon mum Natasha Sale.
The mum of four, who was diagnosed with cervical cancer in 2016, launched the online petition in August last year.
Ms Sale, from Newton Abbot, achieved more than 78,000 signatures before she died in December.
Her friends and family continued her campaign after her death - with the petition reaching 100,000 signatures earlier this month, and it now having almost 130,000 supporters.
Writing in response to her petition in September, the government said it had "accepted the UK National Screening Committee recommendation that the first invitation for cervical screening should be offered at age 25".
It said cervical cancer in women under that age was very rare.
The issue will be debated by MPs in parliament on Monday.
"By reducing the age of smear tests and cervical screenings today, we can save lives, we can tackle cell changes early and prevent cervical cancer. If I can do anything with my life, I want to make this change happen."