A Twitter account thought to be run by Zanu-PF supporters alleges that Emmerson Mnangagwa has been made interim president.
The 75-year-old was sacked from his post as vice-president for what the government called "traits of disloyalty".
At the time, his removal was seen as making it more likely that President Mugabe's wife, Grace, would follow in her husband's footsteps as leader of Zimbabwe.
She had earlier called on her husband to remove his vice-president.
You can read our story on his sacking here.