The first minister responded to criticism from the Scottish Conservatives about funding for hospitality businesses they are yet to receive which was promised to them before Christmas.
Ms Sturgeon said the government and local authorities were working to get the money to companies as soon as possible, and that money would reach hospitality businesses once they completed declaration forms.
Anas Sarwar, Labour's leader, asked about the impact of Covid on the health service. He said the problems it was facing were getting worse, not better.
The first minister said the Delta and Omicron variants had been "blows that we weren't necessarily anticipating". She added that she hoped recovery efforts could escalate and accelerate when Covid is back under control.
Labour MSPs raised concerns about NHS Lanarkshire, which they said has "reached crisis levels".
Ms Sturgeon said that although the level had been escalated in Lanarkshire, it was not in the most serious level of its GP escalation framework. The government has asked the board to review this weekly, she added. She said the decision made by NHS Lanarkshire was to allow access to essential GP services at a time of unprecedented demand and staff absences to be maintained.
Responding to a top Tory minister's comments that the leader in Scotland, Douglas Ross, was a lightweight figure in the party, Ms Sturgeon said that even she was not as derogatory about Mr Ross as his colleagues at Westminster.
The first minister said if Scotland became independent it would mean the country did not have to put up with being treated like something "on the sole of Westminster's shoe".
Fast-track pathways for cancer diagnosis
Tory MSP Brian Whittle asks about cancer diagnosis numbers now compared with pre-pandemic levels.
Mr Whittle speaks of a friend who has been diagnosed with an aggressive prostate cancer at stage three having waited six months for tests.
He asks for better data collection to improve planning for recovery strategies.
The FM says figures in November showed the number of people diagnosed in earlier stages of cancer were lower than before Covid.
SNP MSP Elena Whitham asks about three-hour diagnostic centres that the first minister mentioned were being developed.
Ms Sturgeon said the urgent suspected cancer pathway refers people with traditional and more common symptoms of cancer. She says the early cancer diagnostic centres will provide primary care and a fast-track pathways for people with non-specific symptoms such as weight loss and fatigue.
BreakingSelf-isolation time in England cut to 'five full days'
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The length of time people who have tested positive for Covid must isolate for is being cut to five full days in England from Monday, Health Secretary Sajid Javid announces.
She says people in Lanarkshire are "very afraid" of becoming sick and many have been on waiting lists for treatment since before the pandemic.
She says the "code black" situation has been ongoing for 12 weeks and asks for an urgent meeting with the health secretary and all MSPs in Lanarkshire.
She asks what she should tell constituents who are reaching for the Samaritans because they can't get through to GP surgeries and can't go to A&E?
The first minister says the key to returning to normal is getting and keeping Covid under control. She says in NHS Lanarkshire it is about maintaining access to essential GP services at a time of unprecedented demand and staff absences.
She says community pharmacies can be used, along with NHS Inform and adds that this is a short-term measure and all services will get back to normal as soon as possible.
FM insists she is not as derogatory about Ross as his colleagues are
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SNP MSP Audrey Nicoll asks if the "unmasked disdain" the Tory government has shown for their colleagues in Scotland makes it clear Scotland needs to become an independent country.
Nicola Sturgeon says even she is not as derogatory about Douglas Ross as his colleagues at Westminster, referring of course to the "lightweight" comment from Rees-Mogg.
The first minister says the Westminster cabinet has utter contempt for Scotland.
She says if Scotland becomes independent it will mean the country does not have to put up with being treated like something "on the sole of Westminster's shoe".
Back to the Conservative leader and he accuses the FM of breaking a promise to businesses to support them by not getting vital funding to them.
He asks why Scottish jobs and businesses are always an afterthought for her and her government?
Ms Sturgeon calls this "nonsense" and says she can't give more money to Scottish businesses because the Scottish government didn't get more money from the UK government.
She says this is money which will get to businesses.
She concludes that Douglas Ross' approach to a global pandemic is "to oppose everything the Scottish government tries to do".
'Why are hospitality businesses being held back?'
Mr Ross brings up Omicron, saying the data is now more positive and that the first minister herself has "accepted that the government's projections were wrong".
He asks why hospitality businesses are being held back by the SNP government and asks how it is safe for tens of thousands to go to stadia, but it is not safe to walk from a seat to the bar in a local pub?
Ms Sturgeon says he must be the only person who did not hear "the howls of hospitality businesses south of the border" about the dire straits they were in. She says the difference in Scotland was that the Scottish government responded in a way much greater than the government in England.
She adds that the projections before Christmas were not wrong. She says they were not accepted as inevitable and by taking action the Scottish government was able to change the course of those projections.
Background: Nightclubs still waiting for funding support
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Nightclub owners have criticised the slow rollout of financial support for their businesses, which have been closed again under Covid restrictions.