The GCSE exam in England is going to be replaced in core subjects by a qualification called the English Baccalaureate Certificate.
A shake-up of the exam system, unveiled by Education Secretary Michael Gove, will mean a single end-of-course exam and one exam board for core subjects.
Pupils beginning secondary school this year will take the first new exams - in English, maths and sciences - in 2017.
Mr Gove said GCSEs were designed "for a different age and a different world".
The education secretary said the changes would modernise the exam system "so we can have truly rigorous exams, competitive with the best in the world, and making opportunity more equal for every child".
Labour's shadow education secretary, Stephen Twigg, attacked the plans as "totally out of date, from a Tory-led government totally out of touch with modern Britain".
He also criticised the repeated leaking of the plans to scrap GCSEs which he said meant that such changes avoided proper parliamentary scrutiny.
Mr Twigg accused the education secretary of trying to introduce changes for future exams while he was still grappling with the "fiasco" of this year's GCSE results.
Leighton Andrews, education minister in Wales, criticised the plans as a "backwards step" - and said that Wales might keep the GCSE.
Single exam board
The changes, now being put out to consultation, will be introduced from 2015 - with the first candidates taking the new-look exams in 2017.
This will initially be in three core subject areas - English, maths and sciences.
This will be extended later to history, geography and languages - with the suggestion in the consultation that Ofqual should look at how this template might be used for a wider range of subjects.
This will mean that GCSEs will continue for some subjects alongside the new English Bacs over a number of years.
There will be one exam board for these English Bac subjects rather than having different exam boards competing with their own versions.
This follows concerns that such competition leads to a "race to the bottom", with an incentive for exam boards to attract more business by making it easier to pass.
These are the same subjects that comprise the existing "English Baccalaureate" - a performance measure of schools already introduced by the government.
These English Bac subjects will be assessed entirely by an external examination, with proposals for an end to all internal assessment.
Despite an earlier leak claiming that there would be a two-tier system - similar to the old O-levels and CSEs - the new qualification will be a single exam for a wide range of abilities.
To allow weaker pupils to catch up, the exam might be taken beyond the age of 16 - with the new exams coming alongside the raising of the leaving age to 18.
The Deputy Prime Minister Nick Clegg said the changes would "raise standards for all our children", but he added that it would "not exclude any children".
The changes in England's examinations mark a widening divide between education systems within the UK - with Wales and Northern Ireland so far not following the changes proposed in England.
The Welsh government says it will not be rushed into following any changes being introduced in England and is carrying out its own separate review into the exam system.
Northern Ireland's education minister John O'Dowd also said that the "direction of travel" had yet to be decided.
"It is disappointing to note that, once again, Michael Gove has failed to discuss in advance with the devolved administrations proposals of such significance on an issue which also concerns here and indeed Wales," said Mr O'Dowd.
In Scotland, pupils take Standard Grades, Highers and Advanced Highers rather than GCSEs and A-levels.
Back to the future?
Brian Lightman, general secretary of the Association of School and College Leaders, said GCSEs needed to be reviewed but bringing back an O-level style exam was not the answer.
"I hope that these proposals are not going to be telling us that we're going to have a system that goes back to something that we used to have in the 1950s, which was suited to a very small part of the population," he said.
But Anthony Seldon, head teacher of Wellington College, applauded the changes: "It is extraordinary that clapped-out GCSEs have been allowed to continue for so long, when their deficiencies have been known to all for 10 or more years.
"What is imperative is that the English Baccalaureate should be a test of the ability of pupils rather than of their teachers, assessing independence of thought and response rather than be a regurgitation of prepared answers, and that it should develop scholarship and curiosity."
The National Union of Teachers warned of an "inherent contradiction" in the government's criticism of GCSEs - saying that it was "nonsensical" to expect higher pass rates from schools while at the same time saying that any such improvement was evidence of exams becoming easier.
Martin Johnson of the ATL teachers' union warned: "The plans for GCSE replacements are hugely simplistic and fail to recognise the complexity of learning and teaching."
Chris Keates, head of the Nasuwt teachers' union said: "The government will have to work hard to ensure that these reforms are not the final nail in the coffin for the provision of a broad and balanced curriculum."
"Tinkering with exams is a cheap and relatively easy lever for governments, which has been used and over-used in the past couple of decades. What would make a real, long-term difference to raising standards for all children would be improving the teaching and learning in all schools - but that's long, and hard, and expensive," said Kevin Stannard of the Girls' Day School Trust.