Pupils and teachers from a special school near Mansfield are heading to Iceland after two years spent raising £40,000.
The group, from Fountaindale School, is due to fly out on Thursday morning and will study the effects of volcanic explosions.
Most of the seven pupils who are going have mobility problems and many use wheelchairs or crutches.
Head teacher Mark Dengel said the trip was the result of meticulous planning.
He said: "It's been a massive fundraising experience. We've had to raise a considerable amount of nearly £40,000 for a trip like this."
Many of the youngsters rarely get to travel because of their additional needs.
Some of them will use the work they do in Iceland to contribute towards their GCSEs.