Bernadette Manca di Nissa (born 27 September 1954) is an Italian operatic contralto who has sung leading roles in the principal opera houses of Italy as well as internationally. She has appeared at La Scala in Milan, La Fenice in Venice, Teatro San Carlo in Naples, and the Maggio Musicale Fiorentino in Florence as well as at the Royal Opera House, Covent Garden and Gran Teatre del Liceu in Barcelona.
Born in Cagliari and a descendant of a noble family, she studied singing privately and later at the Mozarteum University of Salzburg. Initially specializing in Baroque music and Rossini's works (Tancredi, Semiramide, L'Italiana in Algeri, La gazza ladra), she developed a wide-ranging repertoire that includes works by Monteverdi, Handel, Jommelli, Mozart, Gluck (Orfeo ed Euridice), Salieri, Donizetti, Verdi (Falstaff), Puccini, Stravinsky and the 20th-century composer Luigi Nono. She has appeared in the world premières of several of Nono's works, including Quando stanno morendo (1982), Guai ai gelidi mostri (1983), and Prometeo, Tragedia dell'ascolto (1984).