In blood glucose regulation, the hormone insulin plays a key role. When blood sugar rises in the blood, insulin sends a signal to the liver, muscles and other cells to store the excess glucose. Some is stored as body fat and other is stored as glycogen in the liver and muscles. Whereas, if the blood glucose level is too low, the liver receives a message to release some of that stored glucose into the blood. This change is brought about by another hormone produced by the pancreas called glucagon.
This is an example of negative feedback.
|Low glucose||High glucose|
|Effect on pancreas||Insulin not secreted into the blood||Insulin secreted into the blood|
|Effect on liver||Does not convert glucose into glycogen||Converts glucose into glycogen|
|Effect on blood glucose level||Increases||Decreases|