Role of glucagon in control of blood sugar levels – Higher

Negative feedback

In blood glucose regulation, the hormone insulin plays a key role. When blood sugar rises in the blood, insulin sends a signal to the liver, muscles and other cells to store the excess glucose in the form of glycogen in the liver and muscles. Whereas, if the blood glucose level is too low, the liver receives a message to release some of that stored glucose into the blood. This change is brought about by another hormone produced by the pancreas called glucagon.

This is an example of negative feedback.

A flowchart to demonstrate negative feedback

How glucose is regulated

Blood glucose levelEffect on pancreasEffect on liverEffect on blood glucose level
Too highInsulin secreted into the bloodLiver converts glucose into glycogenGoes down
Too lowGlucagon not insulin is secreted into the bloodLiver does not convert glucose into glycogen. Glycogen is converted to glucose.Goes up