Mexico's ususal May Day celebrations have been cancelled all over the country and in the capital, Mexico City, government buildings are closed for the next five days.
Shops, restaurants, bars and gyms have shut down in an attempt to stop the spread of the H1N1 flu virus.
President Calderon has asked Mexicans to stay at home over the holiday weekend.
The health minister says there has been a noticeable drop in the number of people being admitted to hospital with severe flu symptoms, but as the BBC's Stephen Gibbs reports from Mexico City there is still a lot of anxiety.
Only key services such as public transport, supermarkets and hospitals are being kept open.
So, what does that mean for Mexicans obliged to work in such places; flu or no flu?
Susana Seijas went to the airport to find out.
David Cuen works for the BBC's Latin American service and is from Mexico.
What kind of medical facilities are available to people?
First broadcast 1 May 2009
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