Newport Gwent Dragons have been drawn against London Wasps in the Amlin Dhallenge Cup draw.
The Welsh region have also joined in Pool 3 by French club Bayonne and Rugby Mogliano from Italy.
The Dragons will be hoping to go better than their three wins and three losses in last year's pool stage.
London Welsh will replace Newcastle in the draw if they win their appeal to the Rugby Football Union over reaching Avia Premiership criteria.
Amlin Challenge Cup 2012/13 Pools
Gloucester Rugby, London Irish, Bordeaux-Bègles, Mont-de-Marsan
Perpignan, Worcester Warriors, Femi-CZ VEA Rovigo, Bizkaia Gernika RT
London Wasps, Newport Gwent Dragons, Bayonne, Rugby Mogliano
Bath Rugby, Cammi Rugby Calvisano, Agen, Bucharest Wolves
Stade Français Paris, Newcastle Falcons/London Welsh, I Cavalieri Prato, Grenoble
Amlin Challenge Cup Dates
11/12/13/14 October 2012
18/19/20/21 October 2012
6/7/8/9 December 2012
13/14/15/16 December 2012
10/11/12/13 January 2013
17/18/19/20 January 2013
4/5/6/7 April 2013
25/26/27/28 April 2013
Amlin Challenge Cup final:
RDS, Dublin (Friday, 17 May 2013, 20:00 BST)