Leeds Rhinos half-back Danny McGuire will miss the Challenge Cup final with Warrington after being ruled out for up to eight weeks with a knee injury.
The 29-year-old limped out of
Friday's 68-24 victory over Widnes.
Head coach Brian McDermott said: "We are absolutely devastated for Danny that he will miss out on Wembley.
"This is the worst possible news that we could have received so close to the final and clearly we will have to have a major rethink about our tactics."
England international McGuire is the joint top try-scorer in Super League with 199, level with Rhinos legend Keith Senior.
In an interview with the
Super League Show last month
McGuire said he "craved" victory in the Challenge Cup, a competition he has never won.
Leeds take on the Wolves at Wembley on 25 August, looking for their first Challenge Cup win since 1999.