Loughgiel and Slaughtneil will contest this year's Ulster club hurling final on 27 October after their respective semi-final victories on Sunday.
Ulster holders Loughgiel beat Down champions Ballygalget by 1-16 to 1-9 in Owenbeg.
Benny McCarry's goal helped Loughgiel lead 1-8 to 0-4 at the break and Gareth Johnson's goal was unable to inspire a Ballygalget rally.
Derry champions Slaughtneil hammered Lisbellaw 4-18 to 0-7 at Dungannon.
Loughgiel, the 2012 All-Ireland club hurling champions, seized the early initiative through a goal from man of the match Benny McCarry after eight minutes.
Liam Watson hit a 20 metre free short to him and, with the Ballygalget defence napping, he drilled a low shot past Graham Clarke.
The goal gave Loughgiel a cushion they held on to for the remainder of the game.
Shay Casey scored twice from play in the first half with Liam Watson hitting 0-4, three from frees, to stretch the favourites' lead.
Ballygalget had a poor first half and trailed by 1-8 to 0-4 at the interval.
The Down champions were much livelier in the second-half and Gareth Johnson, the star of Down's Christy Ring Cup success this year, grabbed a goal back after 37 minutes.
Fellow Down player Danny Toner 0-4 in the second half but Loughgiel were always comfortable and were not flattered by the seven-point winning margin.
McCarry top-scored with 1-4 for Loughgiel with Watson contributing six points.
D Quinn; P Gillan, N McGarry, R McCloskey; T Coyle, M Scullion, O McFadden; M McFadden, T McCloskey; M Connolly, D Laverty (0-1), E McCloskey (0-1); B McCarry (1-4), S Casey (0-2), L Watson (0-6, 4f)
D McKinley (0-1) for Connolly (HT), B McAuley (0-1) for T McCloskey (50), D McCloskey for E McCloskey (53), S Dobbin for Laverty (58)
G Clarke; S Clarke, S Johnson, P McManus; S Bailie, J McGrath, B Toner; E Clarke, G Clarke; J McManus, D McManus, C Bailie (0-2, 1f); G Dynes (0-1), G Johnson (1-1, 1f), D Toner (0-5, 2f)
J Smyth for S Johnson (30), A Smyth for McManus (45), K McGreevy for Dynes (50)
Eamonn Hasson (Derry)
Ulster Club Hurling Semi-Finals results
Loughgiel 1-16 1-09 Ballygalget
Slaughtneil 4-18 0-07 Lisbellaw