Goals from Will Atkinson and Barry Corr earned 10-man Southend United victory over managerless Portsmouth.
Andy Barcham's 20-yard strike after 90 seconds saw Pompey take the lead in their first match since Guy Whittingham's sacking on Monday.
Southend substitute Cauley Woodrow was sent off after only four minutes on the pitch for elbowing Jed Wallace.
But Atkinson slotted home to bring the visitors level and Corr headed in the winner from John White's cross.
Caretaker manager Andy Awford led off his Pompey players to a chorus of boos after their fifth straight defeat.
VIEW FROM THE DRESSING ROOM
Southend United manager Phil Brown told BBC Essex:
"I didn't enjoy the first half. We came here, we knew there was going to be a big crowd. The last thing we wanted to do was give them something to hang their hats onto.
"Low and behold we are two minutes into the game and they score an absolute world-class goal. We could have been two or three down at half-time.
"We played better football when we went down to 10 men. That's the down side of performance, we actually got a hold of the ball when we went down to 10.
"It looked as if they were on the back foot [at 1-1]. We've got hungry lads at the moment. We weren't having a point. We've got all three."
Portsmouth 40 Carson 05 Devera (Holmes - 85' ) 33 Potts (Maloney - 91' ) 13 Ertl 36 Whatmough Booked 06 Bradley 07 Barcham 20 Cooper 10 Craddock Booked (Bird - 81' ) 09 Connolly 35 Wallace Substitutes 03 N'Gala 04 East 08 Padovani 11 Holmes 18 Bird 25 Sullivan 30 Maloney Southend United 17 Bentley 02 White 03 Coker 16 Clifford (Laird - 67' ) 15 Kiernan 23 Thompson (Woodrow - 61' Dismissed ) 12 Atkinson 06 Prosser Booked 11 Straker 10 Corr 08 Timlin (Phillips - 90' ) Substitutes 01 Smith 04 Laird 05 Phillips 09 Reid 20 Njie 21 Payne 33 Woodrow
Ref: Keith Hill