First-half goals from Conor Clifford and Luke Prosser earned Southend victory at Oxford United.
Clifford opened the scoring with a strike from outside the box and Prosser doubled their lead with a close-range header from Kevan Hurst's free kick.
Oxford pushed to get back in the game, but Daniel Bentley saved headers from James Constable and Michael Raynes.
Southend could have increased their lead, but Ryan Clarke saved well from Cauley Woodrow in a one-on-one.
VIEW FROM THE DRESSING ROOM
Southend United manager Phil Brown told BBC Essex:
"[A win was a] long time overdue, to tell you the truth. There were two goals scored and there could have been a lot more.
"It's nice for Conor [Clifford] - he's only a young lad and when he was left out for a couple of games, he was disappointed.
"It's up to us to build them up and when they cross the white line they are ready for action. Conor showed that today.
"He showed a tremendous tenacity, he put his foot in when it needed to be put in, and got himself a goal."
Oxford United 01 Clarke 04 Raynes 03 Newey 19 Mullins 13 Hunt 11 Potter 14 Hall Booked (Davies - 70' ) 07 Rigg (O'Dowda - 70' ) 17 Rose 08 Kitson 10 Smalley (Constable - 55' ) Substitutes 18 Davies 09 Constable 37 Ruffles 15 Williams 21 Crocombe 34 Bevans 35 O'Dowda Southend United 17 Bentley 23 Thompson 02 White 03 Coker Booked 06 Prosser 12 Atkinson 18 Leonard 16 Clifford 14 Hurst (Straker - 88' ) 33 Woodrow (Reid - 85' ) 10 Corr Substitutes 01 Smith 09 Reid 24 Auger 21 Payne 11 Straker 08 Timlin
Ref: Steve Martin