Wales produced a repeat of their Cardiff comeback to deny Gordon Strachan a winning start to his competitive Scotland managerial career.
Scotland started poorly but led through Grant Hanley's first-half header.
Wales' Gareth Bale had to be taken off, but Aaron Ramsey equalised from the spot as Robert Snodgrass was sent off.
And with the Scots reeling, Hal Robson-Kanu rose unchallenged to head home the winning goal for Wales, who had Ramsey sent off in injury time.
The victory lifts Wales up to third place in Group A but the Scots find themselves adrift at the bottom with no wins and just two points from five games.
The match ended in a similar fashion to Wales' 2-1 win in Cardiff back in October, as Chris Coleman's side came from behind to strike two late goals after Scotland needlessly conceded a penalty.
Wales 2-1 Scotland October 2012
- 27 mins: James Morrison gives Scotland the lead.
- Steven Fletcher doubles Scotland's advantage but it's incorrectly disallowed.
- 81 mins: Gareth Bale equalises from the spot for Wales after Shaun Maloney's foul.
- 89 mins: Bale scores a wonder-goal to secure all three points.
Their comeback on this occasion was all the more impressive given Bale's withdrawal at half-time.
Coleman's side played the better football for large swathes of the game, but Strachan will be bitterly disappointed that having clawed their way into a winning position, it was surrendered.
Wales certainly came out the blocks quicker and almost caught the Scots flat-footed as they threatened to take the lead inside a minute.
Ponderous defending allowed Ramsey the opportunity to power in a drive, which Hanley did superbly to block and a soft-looking free kick given against Craig Bellamy, with Allan McGregor grounded, brought an immediate end to the danger.
But there was a less welcome respite for the Scots moments later, as Steven Fletcher crumbled in agony following an innocuous aerial challenge with Ben Davies and had to be replaced by Kenny Miller.
Hanley epitomised the nervousness seemingly coursing through the Scotland side as he misjudged a ball back to McGregor and only just managed to atone by heading clear.
Almost quarter of the game had passed before Scotland fashioned a chance. Chris Burke's deep cross found Miller, but the striker's header flew over.
Fifa 2014 World Cup Qualifying Group A
Burke, who had excelled in Strachan's first game in charge against Estonia, twice blew chances to pick out well-placed team-mates in front of goal, with too many Scots passes finding Welsh feet.
Bellamy and Bale were denied in quick succession by the bravery and quick reactions of McGregor, but Scotland were gradually finding their way into the game.
And though Boaz Myhill was untested by two more Miller headers, he was motionless as the Scots took the lead in first-half injury time.
Mulgrew curled a corner from the right to the back post and Hanley, brilliantly freeing himself from the shackles of Sam Ricketts, headed into the net from just a few yards.
Scotland emerged after the break a far brighter side than the one that had started the game, no doubt buoyed by the goal and the non-appearance of Bale for the second period.
Their initiative was almost rewarded by a beautifully struck Snodgrass effort, which thudded back off Myhill's post.
But this Wales side is not one to feel sorry for itself and though penalty claims for a handball by Hanley were hopeful, they were denied an equaliser when the referee Antony Gautier deemed McGregor had been fouled before substitute Andy King - on the park seconds before - swept into the net.
The game was turned on its head in a three-minute spell, starting with a foul by Snodgrass on Chris Gunter that brought him a second yellow card and - after a delay - a correctly-awarded penalty to Wales.
Ramsey hammered it in off the crossbar and with the Scots dazed, they were punished again as King floated in a cross from the right for Robson-Kanu to head emphatically past McGregor.
Scotland failed to threaten an equaliser, though James McArthur was cynically hauled down by Ramsey in the dying seconds, leading to the Welshman seeing a straight red.
Sadly for Scotland, Shaun Maloney blasted the free kick from 22 yards well over and Wales were left to take the acclaim of their fans.
- 01 McGregor
- 02 Hutton
- 03 Mulgrew
- 04 G Hanley Booked
- 05 Caldwell
- 06 Dorrans (Adam - 63' )
- 07 Snodgrass Dismissed after an earlier booking
- 08 McArthur
- 10 Maloney
- 11 Burke (Rhodes - 86' )
- 09 Fletcher (Miller - 4' Booked )
- 12 Gilks
- 21 Marshall
- 14 Whittaker
- 15 Webster
- 23 R Martin
- 13 Mackay-Steven
- 16 Adam
- 19 Commons
- 22 Bannan
- 17 Naismith
- 18 Miller
- 20 Rhodes
- 01 Myhill
- 02 Gunter
- 03 Davies
- 05 Ricketts
- 06 Williams
- 04 Ledley (Church - 89' )
- 07 Collison (King - 58' )
- 09 Robson-Kanu Booked
- 10 Ramsey Dismissed after an earlier booking
- 11 Bale (Williams - 45' )
- 08 Bellamy
- 12 Price
- 21 fon Williams
- 13 Lynch
- 15 Collins
- 23 Nyatanga
- 14 Richards
- 16 King
- 17 Vaughan
- 20 Williams
- 18 Church
- 19 Vokes
- 22 Easter
Live Text Commentary
Full Time The final whistle is blown by the referee.90:00 +3:46
Shaun Maloney fires a strike on goal direct from the free kick.90:00 +3:46 Dismissal
Dismissal Aaron Ramsey sent off.90:00 +3:41
Aaron Ramsey concedes a free kick for a foul on James McArthur.90:00 +3:01
The assistant referee signals for offside against Kenny Miller. Aaron Ramsey restarts play with the free kick.90:00 +2:20
Charlie Adam takes a shot. Blocked by Samuel Ricketts.90:00 +0:52
Craig Bellamy has a curled shot. James McArthur gets a block in.89:10
Foul by Charlie Adam on Hal Robson-Kanu, free kick awarded. Aaron Ramsey takes the free kick.88:14 Substitution
Substitution Simon Church joins the action as a substitute, replacing Joe Ledley.87:55
Gary Caldwell sends in a cross, Andy King manages to make a clearance.87:39
The ball is sent over by Charlie Mulgrew, clearance made by Ashley Williams.85:34
Short corner taken by Craig Bellamy from the left by-line.85:34 Substitution
Substitution Jordan Rhodes joins the action as a substitute, replacing Christopher Burke.84:27
Andy King takes a shot. Save made by Allan McGregor.83:25
The ball is sent over by Christopher Burke, Ashley Williams manages to make a clearance.81:48
Foul by Charlie Adam on Andy King, free kick awarded. Direct free kick taken by Andy King.76:50
Unfair challenge on Craig Bellamy by Gary Caldwell results in a free kick. Aaron Ramsey takes the free kick.76:08
Charlie Adam concedes a free kick for a foul on Aaron Ramsey. Ben Davies takes the free kick.73:30
Andy King provided the assist for the goal.73:30 Goal scored
Goal! - Hal Robson-Kanu - Scotland 1 - 2 Wales Hal Robson-Kanu scores a headed goal from inside the six-yard box. Scotland 1-2 Wales.
Andy King crosses the ball,72:06
Assist by Chris Gunter.72:06 Goal scored
Goal! - Aaron Ramsey - Scotland 1 - 1 Wales Power penalty scored by Aaron Ramsey. Scotland 1-1 Wales.70:42 Dismissal
Dismissal Robert Snodgrass is sent off by the referee.70:13
The ball is delivered by Chris Gunter, Robert Snodgrass concedes a Penalty for a foul on Chris Gunter.67:59
Strike comes in from Craig Bellamy from the free kick, Allan McGregor makes a save.67:59 Booking
Booking Grant Hanley goes into the referee's book.67:40
Grant Hanley concedes a free kick for a foul on Jonathan Williams.66:54
Shaun Maloney gives away a free kick for an unfair challenge on Andy King. Direct free kick taken by Andy King.66:05
James McArthur concedes a free kick for a foul on Joe Ledley. Andy King takes the free kick.65:15
Jonathan Williams fouled by Charlie Adam, the ref awards a free kick. Aaron Ramsey takes the free kick.64:25
Foul by Samuel Ricketts on Kenny Miller, free kick awarded. Direct free kick taken by Charlie Mulgrew.63:33
Shaun Maloney crosses the ball, clearance by Joe Ledley.62:50
Shaun Maloney takes the inswinging corner, clearance by Hal Robson-Kanu.62:50 Substitution
Substitution Charlie Adam comes on in place of Graham Dorrans.61:27
Ben Davies takes a shot. Blocked by Grant Hanley.60:44
A cross is delivered by Charlie Mulgrew, clearance made by Samuel Ricketts.59:29
Ben Davies crosses the ball, Charlie Mulgrew manages to make a clearance.58:30
Hal Robson-Kanu gives away a free kick for an unfair challenge on Alan Hutton. James McArthur takes the free kick.57:53
Jonathan Williams sends in a cross, Andy King concedes a free kick for a foul on Allan McGregor. Allan McGregor restarts play with the free kick.57:45
Craig Bellamy decides to take the corner short.57:24 Substitution
Substitution (Wales) makes a substitution, with Andy King coming on for Jack Collison.56:48
Chris Gunter takes a shot. Blocked by Grant Hanley.55:24
Craig Bellamy is ruled offside. Indirect free kick taken by Allan McGregor.54:19
Craig Bellamy takes a inswinging corner from the left by-line to the near post, Charlie Mulgrew makes a clearance.54:01
Corner taken by Craig Bellamy.53:50
Craig Bellamy produces a cross, clearance made by Gary Caldwell.53:31
Robert Snodgrass has an effort at goal from the edge of the area striking the post.53:18
Shaun Maloney decides to take the corner short.52:55
Robert Snodgrass has an effort at goal from 18 yards. Blocked by Samuel Ricketts.52:45
The ball is crossed by Shaun Maloney, Samuel Ricketts manages to make a clearance.52:14
Graham Dorrans fouled by Joe Ledley, the ref awards a free kick. Robert Snodgrass restarts play with the free kick.51:12 Booking
Booking Kenny Miller goes into the book.50:54
Shot by Graham Dorrans from outside the area goes high over the crossbar.50:42
A cross is delivered by Alan Hutton.49:22
Hal Robson-Kanu sends in a cross, clearance by Charlie Mulgrew.48:52
Robert Snodgrass fouled by Joe Ledley, the ref awards a free kick. Charlie Mulgrew takes the direct free kick.48:18
Craig Bellamy takes a shot. Gary Caldwell gets a block in.48:07
The ball is swung over by Ben Davies.48:00
Hal Robson-Kanu produces a cross.47:38
The ball is sent over by Shaun Maloney, Boaz Myhill makes a save.46:14
Jack Collison concedes a free kick for a foul on Robert Snodgrass. The free kick is swung in left-footed by Charlie Mulgrew, clearance by Samuel Ricketts.45:01
The referee starts the second half.45:00 +3:10 Half time
Half Time The players leave the pitch at half time.45:00 +2:24
Free kick taken by Gary Caldwell.45:00 +2:24 Booking
Booking Aaron Ramsey is shown a yellow card.45:00 +2:18
Free kick awarded for an unfair challenge on Shaun Maloney by Aaron Ramsey.45:00 +1:02
Assist on the goal came from Charlie Mulgrew.45:00 +1:02 Goal scored
Goal! - Grant Hanley - Scotland 1 - 0 Wales Grant Hanley finds the net with a headed goal from inside the six-yard box. Scotland 1-0 Wales.45:00 +0:26
Charlie Mulgrew takes the inswinging corner,45:00 +0:18
The ball is sent over by Charlie Mulgrew, Ben Davies makes a clearance.45:00 Substitution
Substitution Gareth Bale goes off and Jonathan Williams comes on.44:32
Aaron Ramsey challenges Robert Snodgrass unfairly and gives away a free kick. Free kick taken by Graham Dorrans.42:43
The official flags Craig Bellamy offside. Direct free kick taken by Allan McGregor.40:36
Free kick awarded for a foul by Grant Hanley on Gareth Bale. Boaz Myhill takes the free kick.40:00
Ben Davies concedes a free kick for a foul on Christopher Burke. Direct free kick taken by Gary Caldwell.39:14
A cross is delivered by Chris Gunter, Grant Hanley manages to make a clearance.37:49
Joe Ledley gives away a free kick for an unfair challenge on Robert Snodgrass. The free kick is swung in left-footed by Charlie Mulgrew, Boaz Myhill makes a save.34:53
Samuel Ricketts challenges Kenny Miller unfairly and gives away a free kick. Free kick taken by Graham Dorrans.32:44
Corner from left by-line taken by Shaun Maloney.32:36
The ball is swung over by Christopher Burke, clearance made by Chris Gunter.31:46
Charlie Mulgrew crosses the ball, Kenny Miller produces a header from deep inside the six-yard box that clears the crossbar.30:56
Gary Caldwell takes the direct free kick.30:56 Booking
Booking Hal Robson-Kanu receives a yellow card.30:41
Hal Robson-Kanu concedes a free kick for a foul on Christopher Burke.29:36
Gareth Bale fouled by James McArthur, the ref awards a free kick. Direct free kick taken by Aaron Ramsey.28:07
A cross is delivered by Robert Snodgrass, clearance made by Ben Davies.25:43
Gareth Bale takes a shot. Save by Allan McGregor.25:34
A cross is delivered by Hal Robson-Kanu, Allan McGregor manages to make a clearance.24:52
Craig Bellamy sends in a cross, clearance by Charlie Mulgrew.21:48
Centre by Christopher Burke, Kenny Miller has a headed effort from close range and clears the bar.18:26
The ball is swung over by Hal Robson-Kanu, Alan Hutton gets a block in.17:57
The assistant referee signals for offside against Craig Bellamy. Grant Hanley takes the free kick.16:35
The referee gives a free kick against Craig Bellamy for handball. Shaun Maloney restarts play with the free kick.15:46
Craig Bellamy crosses the ball, Grant Hanley manages to make a clearance.15:14
Corner taken by Craig Bellamy from the right by-line played to the near post.14:59
Gareth Bale takes a shot. Blocked by Grant Hanley.13:34
Unfair challenge on Joe Ledley by James McArthur results in a free kick. Free kick crossed left-footed by Gareth Bale, blocked by Robert Snodgrass.11:27
Foul by Graham Dorrans on Craig Bellamy, free kick awarded. Gareth Bale crosses the ball in from the free kick, Allan McGregor makes a save.10:06
Samuel Ricketts takes the direct free kick.10:06 Booking
Booking Robert Snodgrass is given a yellow card.9:54
Chris Gunter fouled by Robert Snodgrass, the ref awards a free kick.6:58
Robert Snodgrass gives away a free kick for an unfair challenge on Joe Ledley. Direct free kick taken by Aaron Ramsey.6:02
Kenny Miller is flagged offside by the assistant referee. Aaron Ramsey takes the indirect free kick.5:39
Unfair challenge on Kenny Miller by Samuel Ricketts results in a free kick. Direct free kick taken by Graham Dorrans.3:50 Substitution
Substitution Kenny Miller replaces Steven Fletcher.1:44
Foul by Hal Robson-Kanu on Allan McGregor, free kick awarded. Free kick taken by Allan McGregor.0:42
Aaron Ramsey takes a shot. Grant Hanley gets a block in.0:00
The ref blows the whistle to begin the match.
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