Two goals by Arouna Kone lifted Wigan Athletic out of the bottom three and increased 10-man Reading's relegation fears at the Madejski Stadium.
The Ivory Coast striker opened the scoring when Maynor Figueroa's header hit his chest and flew into the net.
Kone made it 2-0 moments later with a sublime finish following Jean Beausejour's defence-splitting pass.
Reading had bad day - McDermott
Figueroa completed the scoring, before falling victim to a dreadful Pavel Pogrebnyak challenge, who was sent off.
Pogrebnyak could have broken Figueroa's ankle and the Russian's dismissal added to manager Brian McDermott's problems.
McDermott knows his side must improve quickly if they are to stay up, particularly as his team's remaining 11 games include trips to Everton, Manchester United and Arsenal. They also have to host Liverpool and Manchester City.
Wigan arrived at the Madejski Stadium with a
in their previous 13 league outings and 51 goals conceded in 26 top-flight outings.
No other team had conceded more in the Premier League yet it was Reading's back line who played like novices.
Martin FisherMatch of the Day commentator
Wigan climb out of the bottom three after a dominant display ended Reading's impressive recent home form. Royals boss Brian McDermott will want to erase this quickly - particularly as his side have some tough looking games on the horizon
It would have been much worse for the Royals but for goalkeeper Adam Federici, the Australian diving full stretch to deny Franco Di Santo following a powerful early run by the Argentina striker.
This page is best viewed in an up-to-date web browser with style sheets (CSS) enabled. While you will be able to view the content of this page in your current browser, you will not be able to get the full visual experience. Please consider upgrading your browser software or enabling style sheets (CSS) if you are able to do so.