Sheffield Wednesday got their sixth win in nine Championship matches to inflict Brighton's first league defeat of 2013.
Leroy Lita put the Owls ahead early on, before Brighton's Ashley Barnes was sent off for kicking Kieran Lee.
Danny Pugh then put Wednesday 2-0 up and, although Andrea Orlandi pulled one back after the break, Michail Antonio wrapped up the victory for the hosts.
The game was marred by a late fracas involving players and staff from both benches sparked by a Pugh foul.
His heavy challenge on Inigo Calderon and subsequent booking sparked a furious reaction from the visiting bench and Owls boss Dave Jones was sent to the stands as stewards and police tried to restore order.
The hosts took the lead with just five minutes gone as Swansea loanee Lita acrobatically volleyed home from Antonio's cross.
Brighton's task was made all the more difficult when Barnes was dismissed and from the the subsequent free-kick, on-loan Leeds midfielder Pugh found the bottom corner.
Despite their numerical disadvantage, Brighton reduced the deficit after 54 minutes when Craig Mackail-Smith pulled back for Orlandi to convert.
But their joy was short-lived as within two minutes Antonio restored Wednesday's advantage with a scrappy close-range finish for his seventh goal of the season.
Pugh's foul on Calderon after 70 minutes preceded a lengthy stoppage in play as the away bench demonstrated their anger at the fact Pugh had only been given a yellow by referee Simon Hooper.
Brighton manager Gus Poyet on the red card:
"In football sometimes you do things that you regret after, but [I have] nothing to complain about.
"I think you would normally probably say you're not happy with him [Barnes].
"Angry? It's difficult to say because I played football, I know when you're on the pitch you do things which sometimes you regret after but I was one of those players so I'm not going to say anything to Ashley Barnes - I hope it doesn't happen too much."
Sheffield Wednesday manager Dave Jones:
"Things happen within a game. The sending-off was pivotal in it as well - and deservedly so, the lad stamped on him.
"Then I just felt every challenge we made, they [Brighton] were trying to even it up and I didn't think that was right and that's what the fracas was over. It's handbags at the end of the day, it's done and dusted now, it's over.
"I think the referee did the right thing just to calm it all down because it would have just carried on. I'll see what he puts in his report and if he gets it right."
- 01 Kirkland
- 02 Buxton
- 04 Gardner
- 32 Llera
- 07 Antonio
- 15 Helan (Madine - 83' )
- 19 Pugh Booked
- 20 Lee
- 25 Prutton Booked
- 28 Coke
- 24 Lita (Semedo - 90' )
- 43 Bywater
- 05 Taylor
- 14 Mattock
- 06 Semedo
- 11 J Johnson
- 16 McCabe
- 09 Madine
Brighton & Hove Albion
- 29 Kuszczak
- 06 El-Abd Booked
- 14 Calderon
- 20 Upson
- 28 Bridge
- 04 Hammond
- 11 Orlandi
- 21 David Lopez
- 26 Bridcutt (Mackail-Smith - 46' )
- 09 Barnes Dismissed
- 19 Ulloa Booked (Vicente - 62' )
- 16 Ankergren
- 02 Bruno
- 15 Vicente
- 18 Dicker
- 25 LuaLua
- 07 Hoskins
- 12 Mackail-Smith
Live Text Commentary
Full Time The referee brings the game to a close.90:00 +3:52
Andrea Orlandi takes the inswinging corner, clearance made by Anthony Gardner.90:00 +2:53 Substitution
Substitution Jose Semedo replaces Leroy Lita.89:19
Free kick awarded for an unfair challenge on Wayne Bridge by Gary Madine. Matthew Upson restarts play with the free kick.87:21
Adam El-Abd challenges Leroy Lita unfairly and gives away a free kick. Michail Antonio takes the direct free kick.86:13
Corner from the right by-line taken by Danny Pugh, Miguel Llera gives away a free kick for an unfair challenge on Tomasz Kuszczak. Free kick taken by Tomasz Kuszczak.84:39
Gary Madine concedes a free kick for a foul on Inigo Calderon. Adam El-Abd restarts play with the free kick.83:29
Foul by Gary Madine on Moreno David Lopez, free kick awarded. Direct free kick taken by Moreno David Lopez.81:47
Inswinging corner taken from the right by-line by Danny Pugh, save by Tomasz Kuszczak.81:47 Substitution
Substitution Jeremy Helan goes off and Gary Madine comes on.81:47
Michail Antonio takes a shot. Matthew Upson gets a block in.80:46
Jeremy Helan crosses the ball. The ball is crossed by Lewis Buxton, Giles Coke has a volleyed shot. Save by Tomasz Kuszczak.78:54 Booking
Booking Caution for Adam El-Abd.78:36
Unfair challenge on Michail Antonio by Adam El-Abd results in a free kick. Direct free kick taken by Danny Pugh.77:45
Lewis Buxton gives away a free kick for an unfair challenge on Matthew Upson. Free kick taken by Tomasz Kuszczak.75:56
Adam El-Abd gives away a free kick for an unfair challenge on Leroy Lita. Danny Pugh takes the free kick.74:52
Centre by Moreno David Lopez, Giles Coke makes a clearance. Inswinging corner taken by Moreno David Lopez, Shot from just outside the box by Moreno David Lopez goes over the target.74:38
Miguel Llera gives away a free kick for an unfair challenge on Andrea Orlandi. Moreno David Lopez takes the direct free kick.69:02 Booking
Booking Danny Pugh booked.68:37
Danny Pugh gives away a free kick for an unfair challenge on Inigo Calderon. Free kick taken by Inigo Calderon.
Inswinging corner taken by Rodriguez Vicente from the right by-line.64:43
Effort from outside the area by Leroy Lita goes wide right of the goal.61:42 Substitution
Substitution (Brighton) makes a substitution, with Rodriguez Vicente coming on for Jose Ulloa.61:29
Shot from just outside the box by Kieran Lee goes over the bar.60:30
Shot from 25 yards from David Prutton. Save by Tomasz Kuszczak.55:28
Danny Pugh provided the assist for the goal.55:28 Goal scored
Goal! - Michail Antonio - Sheff Wed 3 - 1 Brighton Michail Antonio scores a goal from close in low into the middle of the goal. Sheff Wed 3-1 Brighton.54:45
Inswinging corner taken left-footed by Danny Pugh,53:25 Goal scored
Goal! - Andrea Orlandi - Sheff Wed 2 - 1 Brighton Andrea Orlandi fires in a goal from deep inside the penalty box low into the middle of the goal. Sheff Wed 2-1 Brighton.52:18
Inigo Calderon sends in a cross, blocked by Danny Pugh.50:51
Effort from deep inside the area by Jose Ulloa misses to the right of the goal.49:39
Giles Coke concedes a free kick for a foul on Jose Ulloa. Direct free kick taken by Moreno David Lopez.48:27 Booking
Booking Jose Ulloa is shown a yellow card.48:20
Jose Ulloa challenges Giles Coke unfairly and gives away a free kick. Chris Kirkland takes the free kick.45:48
Jose Ulloa takes a shot. Blocked by Anthony Gardner. Inswinging corner taken by Andrea Orlandi, Foul by Adam El-Abd on Giles Coke, free kick awarded. Chris Kirkland restarts play with the free kick.45:01
The game restarts for the second half.45:01 Substitution
Substitution Liam Bridcutt leaves the field to be replaced by Craig Mackail-Smith.45:00 +3:29 Half time
Half Time The match has reached half-time.45:00 +1:07
Foul by Anthony Gardner on Jose Ulloa, free kick awarded. Moreno David Lopez takes the direct free kick.43:36
The official flags Michail Antonio offside. Tomasz Kuszczak takes the free kick.42:51
Jose Ulloa gives away a free kick for an unfair challenge on Anthony Gardner. Free kick taken by Chris Kirkland.41:26
The ball is crossed by Lewis Buxton. The ball is crossed by Danny Pugh. Corner from right by-line taken by Danny Pugh.40:44
Foul by Jose Ulloa on Giles Coke, free kick awarded. Free kick taken by Chris Kirkland.39:52
Leroy Lita gives away a free kick for an unfair challenge on Liam Bridcutt. Adam El-Abd restarts play with the free kick.36:41
Giles Coke challenges Jose Ulloa unfairly and gives away a free kick. Inigo Calderon crosses the ball from the free kick right-footed from left channel, Anthony Gardner manages to make a clearance. Andrea Orlandi takes the inswinging corner, clearance made by Anthony Gardner. Corner taken by Moreno David Lopez from the left by-line to the near post, clearance by Jeremy Helan.33:46
Jose Ulloa has an effort at goal from just outside the box which goes wide of the right-hand post.33:46 Goal scored
Goal! - Danny Pugh - Sheff Wed 2 - 0 Brighton Danny Pugh finds the net with a shot from the free kick from 6 yards. Sheff Wed 2-0 Brighton.32:19 Dismissal
Dismissal Ashley Barnes is sent off by the referee for serious foul play.32:18
Unfair challenge on Kieran Lee by Ashley Barnes results in a free kick.27:33
Ashley Barnes challenges Miguel Llera unfairly and gives away a free kick. Free kick taken by Chris Kirkland.26:21
The ball is delivered by Moreno David Lopez, Lewis Buxton manages to make a clearance. Outswinging corner taken left-footed by Andrea Orlandi from the left by-line.25:01
Adam El-Abd fouled by Leroy Lita, the ref awards a free kick. Free kick taken by Liam Bridcutt.24:23
The referee blows for offside against Jose Ulloa. Chris Kirkland restarts play with the free kick.23:50 Booking
Booking Booking for David Prutton for unsporting behaviour.23:22
Ashley Barnes fouled by David Prutton, the ref awards a free kick. Andrea Orlandi takes the direct free kick.19:52
Shot by Moreno David Lopez from outside the box goes high over the crossbar.18:32
Corner taken left-footed by Andrea Orlandi to the near post, clearance by Miguel Llera.17:11
Shot from just outside the box by Michail Antonio goes over the bar.16:31
Foul by Anthony Gardner on Adam El-Abd, free kick awarded. Tomasz Kuszczak takes the free kick.15:45
Inswinging corner taken by Danny Pugh from the right by-line.11:02
Handball decision goes against Michail Antonio. Moreno David Lopez crosses the ball, Jose Ulloa takes a shot. Save made by Chris Kirkland. Corner taken by Andrea Orlandi from the right by-line, free kick awarded for an unfair challenge on Chris Kirkland by Adam El-Abd. Direct free kick taken by Chris Kirkland.10:22
The ball is swung over by Inigo Calderon, Miguel Llera makes a clearance. Inswinging corner taken from the left by-line by Moreno David Lopez, clearance made by Anthony Gardner.8:01
Unfair challenge on Liam Bridcutt by Danny Pugh results in a free kick. Direct free kick taken by Inigo Calderon.7:24
Foul by Dean Hammond on Jeremy Helan, free kick awarded. Anthony Gardner restarts play with the free kick.4:47
Assist on the goal came from Michail Antonio.4:47 Goal scored
Goal! - Leroy Lita - Sheff Wed 1 - 0 Brighton Leroy Lita finds the back of the net with a goal from close in to the top right corner of the goal. Sheff Wed 1-0 Brighton.4:09
Liam Bridcutt fouled by Leroy Lita, the ref awards a free kick. Adam El-Abd takes the free kick.0:00
The game gets underway.
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