Jack Redshaw's last-minute header denied Wycombe their fourth consecutive win and salvaged a point for Morecambe.
Dean Morgan opened the scoring for Wycombe from the edge of the box before Joel Grant was sent off for a rash challenge on Morecambe's Andrew Wright.
Despite their numerical disadvantage, Morgan added a second for the hosts with a close-range effort.
Richard Brodie's effort from close in gave the Shrimps hope before Redshaw's late headed equaliser.
VIEW FROM THE DRESSING ROOM
Morecambe manager Jim Bentley told BBC Radio Lancashire:
"It's a good point in the end, but looking at it in the first half hour, there was only going to be one winner.
"Wycombe were well up for it and we were very lacklustre.
"We gave ourselves an uphill battle, but the sending-off played into our hands, because with 11 players, Wycombe would have beaten us today."
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