Jermain Defoe came off the bench to score a superb late goal and earn England victory over their Euro 2012 conquerors Italy.
Italy started strongly with Daniele De Rossi giving them the lead when he headed in Alessandro Diamanti's corner.
But Roy Hodgson's side replied, also from a corner, Phil Jagielka sending his diving header in on 27 minutes.
The game looked like petering out, but after Ryan Bertrand cleared off the line, Defoe struck on the counter.
Spurs striker Defoe had plenty to do when he was fed by James Milner, but having turned on the edge of the penalty area, he checked inside Ignazio Abate and smashed a shot past Salvatore Sirigu 11 minutes from time.
For Hodgson, it turned what appeared to be a promising evening in Switzerland into a very pleasing one, meaning he has yet to lose a game in open play after seven games in charge.
Butland's historic debut
- Jack Butland became England's youngest goalkeeper at 19 years and 158 days, beating the record of Billy Moon, who was 19 and 222 days when he played against Wales at Crewe in February 1888.
And with a new-look line-up including only Ashley Young from the team that lost to Italy in the European Championship quarter-finals, there were encouraging performances all over the pitch as Hodgson tweaked his formation from 4-4-2 to a more fluid 4-2-3-1.
In a half-full Wankdorf Stadium, a largely inexperienced team included five debutants - Birmingham goalkeeper Jack Butland, Norwich's John Ruddy, Manchester United's Tom Cleverley, Chelsea's Bertrand and Tottenham's Jake Livermore.
But they were guided by a mature midfield cast of Lampard and Michael Carrick, who quietly linked play, before Defoe made an almost immediate impact after coming on to score his 16th goal for his country.
It took the jolt of De Rossi's opener for England to find their rhythm and 19-year-old Butland, who became the youngest goalkeeper to win a full England cap despite having only played as high as League Two, had to be sharp to deny Italy on several occasions.
Nevertheless, 12 minutes after the Roma midfielder headed in from Diamanti's corner, clever work from Adam Johnson led to a corner for England and Lampard's delivery found Jagielka, who stooped low to guide his header in from eight yards for his first senior England goal.
That seemed to settle Hodgson's side. Skipper Lampard, who missed Euro 2012 because of a thigh injury, twice had thumping shots at goal before he fired a free-kick just over.
Ruddy, who also missed the European Championship through injury, replaced Butland at half-time and had to deal with a resurgent Italy as he too adjusted to international football.
He passed his first test well, though, saving to his right from Mattia Destro's effort. Cesare Prandelli's young side then twice wasted good chances soon after.
Having gathered some momentum, Italy were then disrupted by a flurry of substitutions on the hour mark and they almost went behind as first Gary Cahill had a goal disallowed, before Federico Peluso nearly scored in his own net from James Milner's free-kick.
Defoe's strike came immediately after a threat on Ruddy's goal, substitute Bertrand clearing off the line, before Milner led the counter-attack. Once he fed the Spurs striker, Defoe turned, cut inside and unleashed a fearsome shot into the top corner.
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Live Text Commentary
Full Time The referee blows for the end of the match.90:00 +1:21
The referee blows for offside against Manolo Gabbiadini. Indirect free kick taken by John Ruddy.90:00 +0:59
Tom Cleverley challenges Daniele De Rossi unfairly and gives away a free kick. Free kick taken by Daniele De Rossi.89:38
Short corner taken by James Milner.88:05
Marco Verratti crosses the ball, John Ruddy makes a comfortable save.87:28
Jake Livermore challenges Federico Peluso unfairly and gives away a free kick. Free kick taken by Marco Verratti.87:07
A cross is delivered by Ezequiel Schelotto, save by Kyle Walker.86:58
James Milner challenges Marco Verratti unfairly and gives away a free kick. Marco Verratti takes the free kick.86:10
Free kick awarded for an unfair challenge on James Milner by Federico Peluso. Direct free kick taken by Kyle Walker.85:32 Substitution
Substitution Ezequiel Schelotto joins the action as a substitute, replacing Ignazio Abate.85:25 Booking
Booking Booking for Diego Fabbrini for unsporting behaviour.84:28
Ignazio Abate takes a shot. Blocked by Joleon Lescott.84:05
Jermain Defoe has an effort at goal from outside the area which goes wide right of the goal.83:46
Diego Fabbrini fouled by James Milner, the ref awards a free kick. Free kick taken by Diego Fabbrini.83:38 Substitution
Substitution Mattia Destro leaves the field to be replaced by Diego Fabbrini.80:30
Unfair challenge on Davide Astori by Jake Livermore results in a free kick. Davide Astori takes the free kick.78:55
Assist on the goal came from James Milner.78:55 Goal scored
Goal! - Jermain Defoe - England 2 - 1 Italy Jermain Defoe fires in a goal from just outside the penalty area to the top right corner of the goal. England 2-1 Italy.78:42
Andrea Poli takes the outswinging corner, Marco Verratti takes a shot. Kyle Walker makes a brilliant save.78:16
Marco Verratti takes a shot. John Ruddy makes a fantastic save.
Federico Peluso crosses the ball, Ryan Bertrand manages to make a clearance.77:20 Substitution
Substitution Ryan Bertrand comes on in place of Leighton Baines.76:14
Free kick awarded for an unfair challenge on Michael Carrick by Manolo Gabbiadini. Direct free kick taken by James Milner.74:10
Federico Peluso challenges James Milner unfairly and gives away a free kick. Adam Johnson crosses the ball from the free kick left-footed from right wing, Joleon Lescott challenges Daniele De Rossi unfairly and gives away a free kick. Salvatore Sirigu takes the direct free kick.72:06
Ignazio Abate gives away a free kick for an unfair challenge on Tom Cleverley. A cross is delivered by James Milner, Joleon Lescott takes a shot. Blocked by Federico Peluso.71:31
Free kick awarded for a foul by Mattia Destro on Adam Johnson. Free kick taken by Leighton Baines.70:27
Unfair challenge on Angelo Ogbonna by Jermain Defoe results in a free kick. Free kick taken by Angelo Ogbonna.69:59
Ignazio Abate sends in a cross, clearance made by Joleon Lescott.68:13 Substitution
Substitution Jake Livermore is brought on as a substitute for Frank Lampard.67:51 Substitution
Substitution Alberto Aquilani leaves the field to be replaced by Andrea Poli.67:31
Alberto Aquilani produces a right-footed shot from long range which goes wide right of the target.65:40
Outswinging corner taken right-footed by Frank Lampard from the right by-line, free kick awarded for a foul by Joleon Lescott on Federico Peluso. Salvatore Sirigu takes the direct free kick.64:45
A cross is delivered by James Milner, Federico Peluso gets a block in.63:16
Free kick awarded for a foul by Davide Astori on Jermain Defoe. Leighton Baines takes the free kick.60:56 Substitution
Substitution James Milner joins the action as a substitute, replacing Ashley Young.60:56 Substitution
Substitution Joleon Lescott on for Phil Jagielka.60:38
Effort on goal by Ashley Young from outside the penalty box goes harmlessly over the bar.60:24
Daniele De Rossi challenges Tom Cleverley unfairly and gives away a free kick. Direct free kick taken by Ashley Young.59:48
Corner taken by Frank Lampard from the right by-line.59:25
Corner taken by Frank Lampard from the right by-line to the near post, clearance by Alberto Aquilani.59:15
A cross is delivered by Kyle Walker, Federico Peluso gets a block in.57:48 Substitution
Substitution (Italy) makes a substitution, with Marco Verratti coming on for Alessandro Diamanti.57:48 Substitution
Substitution Manolo Gabbiadini comes on in place of Stephan El Shaarawi.57:22
Federico Peluso produces a left-footed shot from close range which goes wide of the left-hand upright.56:58
Centre by Ignazio Abate, Michael Carrick makes a clearance.54:59
Shot by Federico Peluso from a long way out goes over the crossbar.54:07
The ball is sent over by Alessandro Diamanti, Mattia Destro takes a shot. Save made by John Ruddy.53:02
Free kick awarded for an unfair challenge on Alessandro Diamanti by Kyle Walker. Free kick crossed left-footed by Alessandro Diamanti, Phil Jagielka manages to make a clearance.51:09
The assistant referee signals for offside against Mattia Destro. John Ruddy takes the free kick.49:33
Shot by Stephan El Shaarawi. Save by John Ruddy.48:22
Free kick awarded for a foul by Jermain Defoe on Daniele De Rossi. Alberto Aquilani restarts play with the free kick.45:01
The second half kicks off.45:01 Substitution
Substitution Jermain Defoe joins the action as a substitute, replacing Andy Carroll.45:01 Substitution
Substitution Federico Peluso replaces Federico Balzaretti.45:01 Substitution
Substitution John Ruddy is brought on as a substitute for Jack Butland.45:00 +0:10 Half time
Half Time The match has reached half-time.44:28
The ball is delivered by Adam Johnson, Salvatore Sirigu makes a save.42:48
The ball is crossed by Ignazio Abate.40:10
Ashley Young fouled by Davide Astori, the ref awards a free kick. Direct effort from the free kick comes in from Frank Lampard.39:37
The referee blows for offside. Free kick taken by Frank Lampard.39:04
Centre by Alessandro Diamanti, save by Jack Butland.38:38
Ashley Young gives away a free kick for an unfair challenge on Davide Astori. Davide Astori takes the direct free kick.34:22
Michael Carrick produces a drilled right-footed shot from 25 yards. Blocked by Davide Astori.32:42
Ashley Young sends in a cross.32:24
A cross is delivered by Ashley Young, save by Salvatore Sirigu.31:14
Frank Lampard has an effort at goal. Save by Salvatore Sirigu.28:59
Foul by Alessandro Diamanti on Ashley Young, free kick awarded. Phil Jagielka restarts play with the free kick.26:56
Assist on the goal came from Frank Lampard.26:56 Goal scored
Goal! - Phil Jagielka - England 1 - 1 Italy Phil Jagielka finds the back of the net with a headed goal from close range. England 1-1 Italy.26:31
Corner taken right-footed by Frank Lampard,25:22
Inswinging corner taken left-footed by Alessandro Diamanti, comfortable save by Jack Butland.23:31
Inswinging corner taken from the left by-line by Frank Lampard.22:36
Shot from close in by Mattia Destro misses to the left of the target.22:18
Andy Carroll challenges Davide Astori unfairly and gives away a free kick. Free kick taken by Davide Astori.21:27
The referee gives a free kick against Ashley Young for handball. Ignazio Abate takes the direct free kick.21:01
Adam Johnson takes a shot. Salvatore Sirigu makes a save.20:46
Shot from 20 yards from Frank Lampard. Blocked by Ignazio Abate.19:46
Alberto Aquilani takes a shot. Phil Jagielka gets a block in.18:20
The ball is crossed by Kyle Walker, Angelo Ogbonna manages to make a clearance.17:43
The ball is swung over by Alessandro Diamanti, Mattia Destro takes a shot. Jack Butland makes a brilliant save.14:24
Assist on the goal came from Alessandro Diamanti.14:24 Goal scored
Goal! - Daniele De Rossi - England 0 - 1 Italy Daniele De Rossi finds the net with a headed goal from close in. England 0-1 Italy.14:11
Corner taken by Alessandro Diamanti from the right by-line,13:22
Free kick awarded for an unfair challenge on Alessandro Diamanti by Ashley Young. Alessandro Diamanti produces a strike on goal direct from the free kick, save by Salvatore Sirigu.12:02
Free kick awarded for an unfair challenge on Ashley Young by Angelo Ogbonna. Free kick crossed by Frank Lampard, save made by Salvatore Sirigu.10:59
Adam Johnson has an effort at goal. Federico Balzaretti gets a block in.9:54
Corner taken by Frank Lampard from the left by-line, Andy Carroll produces a header from inside the six-yard box that clears the bar.9:45
The ball is crossed by Leighton Baines, Alessandro Diamanti makes a clearance.9:20
Unfair challenge on Ashley Young by Ignazio Abate results in a free kick. Frank Lampard restarts play with the free kick.8:31
A cross is delivered by Andy Carroll.7:55
Inswinging corner taken from the left by-line by Frank Lampard.7:46
Leighton Baines sends in a cross, Ignazio Abate gets a block in.6:20
Free kick awarded for an unfair challenge on Alberto Aquilani by Ashley Young. Alberto Aquilani takes the direct free kick.3:59
The ball is sent over by Ignazio Abate.3:17
Tom Cleverley is penalised for handball and concedes a free kick. Free kick taken by Ignazio Abate.1:44
Daniele De Rossi challenges Tom Cleverley unfairly and gives away a free kick. Michael Carrick restarts play with the free kick.0:28
Corner taken left-footed by Alessandro Diamanti to the near post, Mattia Destro produces a header from close range which goes wide of the left-hand upright.0:00
The game gets underway.
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