Wycombe picked up a comfortable win and ensured that it would not be a happy return to the Football League for York.
Matt Bloomfield put the visitors ahead with a deflected strike from the edge of the area, before Sam Wood's superb 35-yard volley doubled the advantage.
And Stuart Beavon gave the Chairboys a three-goal cushion when he stroked home Stuart Lewis's cutback.
Jason Walker turned in Jonathan Smith's header for the hosts, but it was too little, too late.
VIEWS FROM THE DRESSING ROOM
York City manager Gary Mills told BBC Radio York:
"I don't think we were on our game today. I don't think we played how we play.
"I don't think we were brave enough to play enough out back, I thought we put too many balls down their throats early on in the game, and for me that carried on until half-time.
"They scored a cracking goal for the second, but it's how they get those opportunities in the first place."
Wycombe midfielder Sam Wood told BBC Three Counties Radio:
"They say 'if you don't shoot, you don't score', so I thought I'd let one go and luckily it went in.
"As soon as it fell in front of me, I thought 'I'm just going to bang it'.
"I hit it and it felt nice and I saw it loop over the keeper. I didn't know what to do, whether to celebrate, laugh or whatever.
"Momentum was with them after getting promoted and winning the (FA) Trophy as well. We knew it was going to be tough, but we were clinical, we took our chances."
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Live Text Commentary
Full Time The match has reached full-time.90:00 +4:14
Inswinging corner taken right-footed by Ashley Chambers.90:00 +2:47 Substitution
Substitution (Wycombe) makes a substitution, with Richard Logan coming on for Stuart Beavon.90:00 +0:04
Unfair challenge on Sam Wood by John McReady results in a free kick. Free kick taken by Grant Basey.89:22
Stuart Beavon is caught offside. Michael Ingham takes the indirect free kick.88:40
Foul by Jamal Fyfield on Anthony Stewart, free kick awarded. Nikki Bull takes the indirect free kick.85:42 Substitution
Substitution Dave Winfield comes on in place of Matt Bloomfield.81:36
Shot by Michael Potts from a long way out goes over the crossbar.80:28
Foul by Chris Doig on Leon Johnson, free kick awarded. Matt Spring crosses the ball from the free kick right-footed from left channel, save made by Michael Ingham.76:36
Corner taken by Ashley Chambers from the left by-line, Gareth Ainsworth makes a clearance.75:45 Substitution
Substitution (Wycombe) makes a substitution, with Dennis Oli coming on for Joel Grant.74:03
Corner taken right-footed by Ashley Chambers from the left by-line, Matt Spring manages to make a clearance.72:19
The offside flag is raised against Sam Wood. Michael Ingham takes the indirect free kick.69:01
Free kick awarded for a foul by Chris Doig on Gareth Ainsworth. Strike comes in from Joel Grant from the free kick.68:14 Substitution
Substitution Michael Coulson leaves the field to be replaced by John McReady.67:05
The ball is swung over by Michael Potts, Close range header by Jason Walker goes over the crossbar.66:19
Daniel Parslow takes the direct free kick.66:19 Booking
Booking Matt Spring goes into the book for unsporting behaviour.66:07
Matt Spring gives away a free kick for an unfair challenge on Jason Walker.65:17
Foul by Jason Walker on Anthony Stewart, free kick awarded. Indirect free kick taken by Nikki Bull.
Free kick awarded for a foul by Stuart Lewis on Daniel Parslow. Direct free kick taken by Michael Potts.63:36
Unfair challenge on Daniel Parslow by Stuart Lewis results in a free kick. Michael Ingham restarts play with the free kick.63:17
Michael Coulson takes the outswinging corner, save by Nikki Bull.62:35
The ball is crossed by Chris Doig, Daniel Parslow takes a shot from 12 yards. Nikki Bull makes a save.60:00
Matty Blair takes a shot from close in clearing the crossbar.58:54
Gareth Ainsworth gives away a free kick for an unfair challenge on Chris Smith. Michael Ingham restarts play with the free kick.56:46
Gareth Ainsworth has a drilled shot. Save made by Michael Ingham.56:31
Daniel Parslow fouled by Leon Johnson, the ref awards a free kick. Free kick taken by Chris Smith.55:52 Substitution
Substitution Patrick McLaughlin leaves the field to be replaced by Michael Potts.55:52 Substitution
Substitution Lee Bullock leaves the field to be replaced by Matty Blair.53:52 Goal scored
Goal! - Jason Walker - York 1 - 3 Wycombe Jason Walker fires in a goal from close range to the bottom right corner of the goal. York 1-3 Wycombe.53:15 Booking
Booking Michael Ingham is shown a yellow card for dissent.52:02
The assist for the goal came from Stuart Lewis.52:02 Goal scored
Goal! - Stuart Beavon - York 0 - 3 Wycombe Stuart Beavon fires in a goal from deep inside the penalty box to the bottom right corner of the goal. York 0-3 Wycombe.50:15
Free kick awarded for an unfair challenge on Daniel Parslow by Gareth Ainsworth. Daniel Parslow restarts play with the free kick.47:35
Corner taken right-footed by Michael Coulson, save made by Nikki Bull.47:14
Michael Coulson decides to take the corner short.46:35
Foul by Grant Basey on Michael Coulson, free kick awarded. Chris Doig takes the free kick.45:39
Effort from deep inside the area by Jonathan Smith clears the bar.45:01
The second half begins.45:00 +6:10 Half time
Half Time The match has reached half-time.45:00 +1:29
Outswinging corner taken by Michael Coulson, clearance by Leon Johnson.43:55 Goal scored
Goal! - Sam Wood - York 0 - 2 Wycombe Sam Wood scores a goal from long range to the top left corner of the goal. York 0-2 Wycombe.42:49
Effort from 20 yards by Anthony Stewart. Save by Michael Ingham.41:26
Jason Walker has an effort at goal from deep inside the area missing to the right of the goal.38:44
Corner taken by Michael Coulson, save by Nikki Bull.37:22
Jason Walker has a shot on goal from outside the area which misses right.34:21
The referee gives a free kick against Anthony Stewart for handball. Chris Doig takes the free kick.32:17
Jonathan Smith produces a volleyed right-footed shot from 20 yards. Save made by Nikki Bull.30:07
Corner taken right-footed by Michael Coulson from the right by-line, Stuart Lewis makes a clearance.29:24
Ashley Chambers fouled by Joel Grant, the ref awards a free kick. Free kick crossed right-footed by Michael Coulson, Nikki Bull makes a save.28:29
Michael Coulson has shot on goal from just outside the penalty box which goes wide of the right-hand upright.27:02 Goal scored
Goal! - Matt Bloomfield - York 0 - 1 Wycombe Matt Bloomfield fires in a fantastic goal from the edge of the penalty area to the bottom left corner of the goal. York 0-1 Wycombe.26:02
Leon Johnson restarts play with the free kick.26:02 Booking
Booking Jonathan Smith goes into the referee's book for unsporting behaviour.25:35
Foul by Jonathan Smith on Matt Spring, free kick awarded.23:18
Jonathan Smith gives away a free kick for an unfair challenge on Stuart Lewis. Grant Basey restarts play with the free kick.18:30
Free kick awarded for a foul by Grant Basey on Jason Walker. Daniel Parslow takes the direct free kick.15:50
Foul by Joel Grant on Ashley Chambers, free kick awarded. Chris Doig takes the free kick.14:58
Michael Coulson is ruled offside. Nikki Bull takes the free kick.14:36
Grant Basey is adjudged to have handled the ball. Lee Bullock takes the free kick.12:42
Unfair challenge on Joel Grant by Jason Walker results in a free kick. Sam Wood takes the free kick.11:34
Free kick awarded for an unfair challenge on Gary Doherty by Chris Smith. Sam Wood takes the free kick.10:08
Corner taken short by Ashley Chambers.7:43
Foul by Michael Coulson on Leon Johnson, free kick awarded. Free kick taken by Nikki Bull.6:27
Jamal Fyfield concedes a free kick for a foul on Matt Bloomfield. The free kick is swung in left-footed by Sam Wood, save made by Michael Ingham.0:39
Sam Wood takes the inswinging corner, clearance by Jamal Fyfield.0:00
The game kicks-off.
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