Osano and Antwi were last at Rushden and Dagenham respectively
Luton Town have handed six-month contracts to defenders Curtis Osano and Will Antwi, both free agents.
Kenyan Osano, 24, had spent the last four years at crisis club Rushden and featured 41 times in the Blue Square Bet Premier last season.
Former Crystal Palace trainee Antwi has had spells with Aldershot, Wycombe and most recently Dagenham.
The 28-year-old featured 24 times last term as the Daggers suffered relegation from League One.
Antwi, who has one cap for Ghana, and Reading youth product Osano had been on trial at Kenilworth Road.