"Nobody needs to cry for me, I'm going to be great," Armstrong said.
"I have five great kids and a wonderful lady in my life. My [charitable] foundation is unaffected by all the noise out there.
"I think people understand that we've got a lot of stuff to do going forward. That's what I'm focused on and I think people are supportive of that."
The USADA says it has more than 12 witnesses, up to 10 of whom are believed to be former team-mates of Armstrong, who agreed to testify and give evidence that the Texan used performance-enhancing drugs and encouraged others to do so.
Who decides if Lance Armstrong is guilty?
Matt SlaterBBC sports news reporter
"UCI (International Cycling Union) is the governing body of the sport, and normally they would be the ones who do the stripping of points, prizes and money, all the things that USADA (United States Anti-Doping Agency) have said.
"We are now going to get a row about actually implementing these sanctions and it is going to be messy.
"I think it will almost definitely end up at the Court of Arbitration for Sport."
Armstrong issued a statement on Friday saying he would no longer contest USADA's charges, explaining he was tired of fighting the allegations. He never failed a drugs test.
However cycling's global governing body, the
International Cycling Union (UCI),
has challenged USADA's jurisdiction over doping in the sport, and has the option of appealing against the ruling to the Court of Arbitration for Sport.
It says it will not take any action or comment further until it has received evidence from USADA explaining why Armstrong must lose his titles. He won the Tour de France seven years in a row from 1999. He retired from cycling in 2005 but returned to the sport between 2009 and 2012.
Tour de France organisers said they would wait for the outcome of any stand-off between USADA and the UCI before taking action.
Armstrong says he is no longer bothered about racing, having been beaten in Aspen by 16-year-old rider Keegan Swirbul.
"It's more about staying fit and coming out here and enjoying one of the most beautiful parts of the world, on a beautiful day, on a very hard course," Armstrong said.
Lance Armstrong spoke about the drug allegations in February 2011
Donations to Armstrong's foundation have increased to 20 times their daily average since his ban was implemented, and Armstrong said he was appreciative of the support shown in Colorado.
"The people, like the people who are standing around the course, they voiced their opinion in the last 48 hours and are going to support us," he added.
"There are a lot of good young guys. Cycling is going to be fine."
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