World champion Mark Cavendish won the second stage of the Tirreno-Adriatico, his fourth victory of the season.
The Team Sky rider beat Oscar Freire of Spain and American Tyler Farrar in the final sprint.
He clocked 6 hours, 32 minutes, 32 seconds over the largely flat 230km leg from San Vincenzo to Indicatore.
Australian Matt Goss, Cavendish's former team-mate at HTC-Highroad, retained the overall lead in the Italian coast-to-coast race.
The third stage on Friday takes the riders 178km from Indicatore to Terni.
Cavendish, in his debut season for Team Sky,
won two stages at the Tour of Qatar
triumphed in the Kuurne-Bruxelles-Kuurne