India have dropped Zaheer Khan, Yuvraj Singh and Harbhajan Singh from their squad following their seven-wicket defeat by England in the third Test.
Fast bowler Parvinder Awana and all-rounder Ravindra Jadeja receive their first Test call-ups, while leg-spinner Piyush Chawla replaces Harbhajan.
Sachin Tendulkar, 39, keeps his spot and Mahendra Dhoni remains captain, despite calls for them to be dropped.
India need to win the fourth Test in Nagpur to avoid a series defeat.
"England have beaten India at their own game, despite having lost the toss in their last two matches. They have been playing on subcontinental style pitches, but have emphatically outplayed India. Seven wickets does not really flatter England but that won't matter. It's a terrific turnaround from the first Test."
England lead the series 2-1 and if they avoid defeat will end their
27-year wait for a series win in India
and condemn their hosts to a first home loss since Australia won 2-1 in 2004.
Victory in the final match for Alastair Cook's men would also see India lose three matches in a home series for the first time since West Indies side triumphed 3-0 in 1983.
Dhoni is facing intense pressure, with the
Times of India
calling for him to be dropped, but the wicketkeeper-batsman insists he is the man to take the team forward.
"Leading a side is all about doing it when the team is not doing well, trying to gel them together, back the youngsters and the senior guys.
"The easiest thing for me to do right now is to give up the captaincy and be part of the side, because that's just running away from the responsibility.
"I have to get the team together, and be prepared for the next Test."
Delhi seam bowler Awana, 26, has taken 131 wickets in 40 first-class matches and played against England for India A in a
tour match last month,
taking 0-60 from 12 overs.
Left-hander Jadeja, 24, has played 58 one-day internationals, scoring five half centuries at an average of 28 and taking 57 wickets with his slow left-armers.
Chawla made his Test debut aged only 17 against England in 2006, taking one wicket, but played in only one more Test, against South Africa in 2008, when he took 2-66.
The 23-year-old played the last of his 25 one-day internationals in 2011 and has taken 32 wickets at a cost of 34 in the 50-over game.
"After Ahmedabad, a few basic things were rammed home to the England team. Deep down, they knew they had a better bowling attack than India, but that was never going to do them any good unless they had runs to play with. The tourists worked out what they had to do - bat long, sell your wicket dearly."
Dhoni does not believe that India are at their lowest ebb in his tenure, citing instead whitewash defeats away to both Australia and England.
"We were not really able to compete then. We know what our faults are here, and I think we should be able to rectify them."
Dhoni said his side needed to "retaliate" in Thursday's final Test after being comprehensively outplayed in Kolkata.
"Everybody needs to pull up their socks, give their best and back each other, that's where you show your character," said Dhoni.
"I think the batting order will have to take the responsibility. We need to score more runs to give the bowlers a par total to defend, otherwise it's very difficult and you find yourself under pressure."
Former England coach Duncan Fletcher has also had his critics since taking the same position with India, and has now overseen six Test defeats out of seven home and away against his old team.
Dhoni, however, insists Fletcher is not to blame. "The coach has excellent technical knowledge about batting, and guides the players in the right direction," he said.
"Ultimately, once you cross that rope, you are on your own. That's where we are lacking as of now. It's wrong to question the coach, because we have won quite a few series."
Mahendra Dhoni (capt/wk), Gautam Gambhir, Virender Sehwag, Sachin Tendulkar, Virat Kohli, Ravindra Jadeja, Cheteshwar Pujara, Ravichandran Ashwin, Ashok Dinda, Pragyan Ojha, Ajinkya Rahane, Piyush Chawla, Ishant Sharma, Murali Vijay, Parvinder Awana.
Mahendra Dhoni (capt/wk), Gautam Gambhir, Ajinkya Rahane, Virat Kohli, Rohit Sharma, Suresh Raina, Yuvraj Singh, Manoj Tiwary, R Ashwin, Ravindra Jadeja, Piyush Chawla, Ashok Dinda, Bhuvneshwar Kumar, Laxmipathy Balaji, Parvinder Awana.