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This red chalk on paper drawing dates from around 1506, a period when Leonardo had relatively easy access to human bodies that he could study and dissect.
He believed that, "motion is the cause of everyday life" and always applied his engineer's eye to investigating the way joints and limbs operate. Aware of the idea of opposed forces, he worked hard to establish the groupings of muscles that enable us to perform movements like walking.
The original of this sketch belongs to the British Museum in London and can be viewed online.
 Look For -
Although the sketch includes the abdomen, genitals, leg and feet, it's clear that this sketch is a study of the muscle groups in the upper and lower leg.
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Renaissance medicine