How do we live our lives when suffering from an incurable disease?
Twenty years ago Jane Pugh was diagnosed with polycystic kidney disease. Both her father and grandmother died of PKD, as it's known, when they were 45. Jane herself is now 40 and has begun writing a column for The Times in which she describes living with the disease.
Martha talks to Jane, together with Dr Anand Saggar, consultant in clinical genetics at St George's Medical School in London.