The chief executive of Twycross Zoo, Sharon Redrobe, claims the chimps used in television tea adverts were permanently damaged by their experiences. Mark hears a report from the zoo, which looks after the last remaining TV chimp Chopper. Mark asks whether animals should still be used on screen.
As Scunthorpe family firm Hornsbys celebrates 100 years in business, Mark's talking about memorable bus journeys. He speaks to Josh West, who took part in the BBC's Toughest Place To Be... series; and the author of Great British Bus Journeys, David McKie.
Mark hears a report from Nottinghamshire charity fund-raisers who go door-to-door to recruit donors. Mark asks whether it's time to make cold calling illegal. He speaks to the deputy director of the UK Direct Selling Association, Linda Mills.
Introducing tonight comes from Izzy Marie Hill from Leicester and Mike Grogan from Portsmouth.
Six-year-old Ellie Davidson is battling leukaemia for the second time, but is set to have a potentially life-saving operation within the next week. Hear from BBC Wiltshire's Ben Prater who has been to meet her.