Dotun Adebayo takes you through the night, with interviews about stories from around the world, updates from the BBC's foreign correspondents, and regular news and sport updates.
Including at 1.35am, interviews with big stars and new faces on the music scene with Jamie Stangroom.
There's a look at the week's medical news with Up All Night's doctors, Mark Hamilton or Raj Thakkar.
And from 2.35am, your chance to take part in the Friday phone-in. Call 0500 909 693 [free from most landlines; other networks and mobiles may charge]. Text 85058 [standard rate]. Email firstname.lastname@example.org.