Anita Anand and Giles Dilnot are here with the top political stories of the day.
No one in the coalition thought government was going to be easy. But did they think it would get this bad? Nearly all the high-flyers are nursing a headache. They ask three backbenchers if Mr Cameron's roadshow out of control?
Should we destroy the last of the world's smallpox virus? It still exists behind closed doors in Russia and America.
And take that meat out of your sandwich. Daily Politics looks at what it means to be green in Brighton.
With Anita and Giles for the whole programme is the former UK ambassador to Washington Sir Christopher Meyer and they talk about President Obama's forthcoming visit to Britain.