Scene of Venezuela refinery blast
25 August 2012 Last updated at 13:30 BST
At least 19 people have been killed and dozens more injured in an explosion at Venezuela's biggest oil refinery, according to the local governor, Stella Lugo.
More than 50 people are also understood to been injured and are being treated in local hospitals.
Video footage from Venezuela's Telesur TV showed the scene of the blast.