Mourners react during a funeral for bomb blast victims in Karachi
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Karachi blast brings city to a standstill

4 March 2013 Last updated at 18:22 GMT

The Pakistani city of Karachi is in mourning after a powerful bomb ripped through a mainly Shia Muslim area, killing at least 45 people.

Schools and businesses are closed after a strike was called to protest against the attack in Abbas Town.

Sunday night's explosion destroyed several buildings and set others on fire, sending a huge column of smoke into the sky and causing a power cut in part of the city.

Mike Wooldridge reports.