Pope Benedict talks to astronauts on ISS and Endeavour
21 May 2011 Last updated at 21:45 BST
Pope Benedict XVI has made the first Papal call to astronauts in space.
The pope spoke to the 12 astronauts on board the International Space Station and the space shuttle, Endeavour, telling them he admired their courage.
The Pope spoke from inside the Vatican.
The BBC correspondent in Rome Duncan Kennedy reports.
People speaking in this video are, in order: Pope Benedict XVI; Ronald Garan, astronaut