Bionic pancreas
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Volunteers trialling 2014's medical breakthroughs

30 December 2014 Last updated at 11:07 GMT

A bionic pancreas for people with Type 1 diabetes, and a new drug to treat certain skin cancers - these are just some of the medical milestones reached this year, with the help of volunteers taking part in trials.

In the latest in a series of special reports, the BBC's Victoria Gill has met the patients who have been contributing to some of 2014's most significant breakthroughs.