Pfizer contacts AstraZeneca over takeover bid
28 April 2014 Last updated at 09:46 BST
US drugs giant Pfizer has confirmed it has contacted AstraZeneca over a possible multi-billion pound takeover.
Pfizer said it made an initial approach in January, but after "limited high-level discussions" AstraZeneca discontinued the talks on 14 January.
It said recent market developments had prompted it to approach AstraZeneca for a second time.
If successful, it would be one of the biggest deals in UK corporate history.
The BBC's Business Editor, Kamal Ahmed reports.