Johannes Lupi (c. 1506 – December 20, 1539) was a Franco-Flemish composer of the Renaissance. A representative of the generation after Josquin, he was a minor but skilled composer of polyphony who was mainly active in Cambrai.
His birthplace is unknown, but he served in Cambrai as a choirboy. He lived in Cambrai most of his life, only leaving to attend the university in Leuven, where he was present from 1522 until 1526. In 1527 he became master of the choirboys at the Cambrai cathedral, a position which typically included housing and boarding them in addition to teaching them music. Several times he was fired from his job, but always re-hired again, usually for failing to discipline his charges but also for poor bookkeeping.
Lupi had an unnamed chronic illness which plagued him increasingly in the 1530s—he had to leave his position because of it in 1535—and which caused his early death.
All of his surviving music is a cappella vocal. Only two masses survive, but he wrote numerous motets and chansons; the motets were collected and printed in 1542 by Pierre Attaingnant.