Régine Chassagne (born 18 August 1977) is a Canadian multi-instrumentalist musician and singer, and a founding member of the band Arcade Fire. She is married to co-founder Win Butler.
Régine Chassagne was born in Montreal, Quebec, Canada, and grew up in St-Lambert, a suburb south of Montreal. Her parents, who were of Haitian origin, emigrated from Haiti during the dictatorship of François Duvalier, which is alluded to in the Arcade Fire song "Haiti", in which she sings, Mes cousins jamais nés hantent les nuits de Duvalier ("My unborn cousins haunt Duvalier's nights"). The line is in reference to the relatives who were killed during the Jérémie Vespers massacre.
Chassagne attended the prestigious Collège Jean-de-Brébeuf before earning a B.A. in communication studies at Concordia University in 1998, and went on to study jazz voice briefly at McGill University. She was singing jazz at an art opening at Concordia in 2000 when Win Butler met her and persuaded her to join his band; after line-up changes, only the two of them were left. They married in 2003 and had their first child, a son, on April 21, 2013.