Comments for en-gb 30 Sat 28 Feb 2015 01:36:32 GMT+1 A feed of user comments from the page found at diamond281 I know that the test is a good few years away yet but I'm glad that a test is being researched on. You say that having the knowledge that you have it would be a burden for people. However, I know that for some people it will be a relief to know either way, like people who were infected with blood products in the 1980s, who recieved HIV and Hepatitis C. A lot of them have recieved letters stating that they could be at risk of vCJD. I know this because my Mum was one of those people. I think it would be relief for her and the whole family to find out if she has it or not since its an issue that is always on our minds already! Fri 25 Feb 2011 16:12:54 GMT+1 sensiblegrannie pandatank' at post 1I wonder if what you are saying is nearer to the truth than the more popularized explanations given? Mon 14 Feb 2011 12:36:42 GMT+1 SAH The progress of British scientists in developing an accurate test for vCJD must be applauded. It has the potential to enable early diagnosis of this insidious disease. It may also represent a first step towards developing a screening test for blood donors or for testing people considered at risk for public health purposes. The latter test, however, requires a great deal of additional work and could be several years away from completion.What seems to be lost in the euphoria is the excellent work that has been done by other British scientists at ProMetic Biosciences Ltd in Cambridge, working in collaboration with French and American counterparts, in developing a filter that significantly reduces the risk of transmission of vCJD through blood transfusion. As reported by the BBC, in late 2009, the Advisory Committee on the Safety of Blood, TIssue and Organs "SaBTO", recommended the adoption of a prion reduction filter to pre-treat red blood cells destined for children born since 1 January 1996. Studies evaluating the safety of filtered red cells have just been successfully completed using the P-CaptĀ® filter which has been CE marked and commercially available since 2006. It is laudable that British scientists have made progress on different fronts to address an intractable British public health issue. I would hope that the BBC would join me in encouraging the government to act now to adopt the P-Capt filter for all age groups while supporting future work to develop a screening test for vCJD. This two pronged approach will help improve blood safety and minimise the risk of vCJD transmission through blood transfusion for everyone. Wed 09 Feb 2011 13:03:57 GMT+1 Graham Steel I completely agree with all the points mentioned by concerned attorney.Moreover, as mentioned in the Lancet Manuscript under discussion, there is a distinct COI issue in relation to two of the authors of it:-"Conflicts of interestJC is a director and JC and GSJ are shareholders and consultants forD-Gen (London, UK), an academic spinout company working in the fi eldof prion disease diagnosis, decontamination, and therapeutics. D-Genmarkets the antibody used in this study. All other authors declare thatthey have no confl icts of interest". Sun 06 Feb 2011 11:58:37 GMT+1 concerned attorney It would be excellent news indeed if an early diagnostic test was found for CJD generally. However it appears that the latest news from Professor Collinge relating to a blood test for vCJD is just hype against the latest developments in Japan (as reported on 31st January 2011). Microbiologist Ryuichiro Atarashi and his team of Nagasaki University have developed an assay test known as real time quaking-induced conversion (RT QUIC) which correctly disgnoses CJD more than 83% of the time. If that is right it is more accurate than the alleged blood test developed by Professor Collinge. Furthermore Professor Collinge only seems to refer to diagnosing vCJD which represents less than 15% of all CJD cases. Surely an early diagnostic test is essential for all CJD and not just vCJD. But perhaps Professor Collinge is concentrating on vCJD (which is the minority) because there is a compensation scheme in place for the vCJD victims but not sCJD (which is the majority) or indeed for genetic or iotragenic CJD.Whilst an early diagnostic test is without doubt very desirable what about a treatment or a cure for CJD. The only currently available treatment (although not a cure) is Pentosan Polysulphate (PPS). Professor Collinge and his team at Queen Square refuse to administer PPS on CJD patients even though there are vCJD patients survising as long as 9 and 8 years on this treatment. There is also a sCJD patient surviving for almost 3 years on PPS. What news from Professor Collinge about a treatment and why does Professor Collinge refuse to administer the only treatment currently available? Thu 03 Feb 2011 17:51:53 GMT+1 angelscomeinthrees Pandatank, I heard something years ago about deer getting a variant of CJD and organophosphates being the likely culprit. Thu 03 Feb 2011 16:02:44 GMT+1 pandatank There is a significant body of research pointing towards a different mechanism for vCJD. Prions exist in the body anyway. Research suggests that upsetting the Copper/Manganese balance within naturally occurring prions is what starts these prions creating such problems within the brain and CNS. The reindeer equivalent of CJD occurs in geographic hot spots where the common factor is the existence of manganese mine tailings. There are many commercial reasons why it is preferable for this research to remain in obscurity. Compensation for the "anti British Beef" campaign is just one. The other is the widespread use of chemicals known to have a significant effect in altering this balance, organophosphates being one category. Thu 03 Feb 2011 15:47:02 GMT+1