I'm picking a clean sweep to the southern hemisphere. No surprises there. History suggests that the home nations in particular will struggle. Here are some things to think about:
1. The rules will be refereed in a similar way to the s14 (as I understand it anyway, the rule interpretations have been standardised between hemispheres). It favours the SH sides in that they have been playing that way for months (not sure about the European sides). But NH have an advantage over NZ and Aus in that both these sides are struggling to adapt to live without competition for the ball in the rucks.
2. Most teams chances will be affected by injuries. This is particlualry true for NH teams (e.g. England) where players are at the end of a long season (I talked to a mate of mine who played an English season snadwiched between 2 NZ ones and his body was wreck at the end of 20 months + of continuous rugby).
3. SA have the two top sides in the S14 and players like Bekker and Fourie look like thay have taken another step up.
4. Australia is actually the best performed nation overall in the s14 and have some real talent coming through, particularly in the backs.
5. NZ is a mixed bag. Only Canterbury have performed well in the s14. However, new players are starting to come through (Guilford, Dagg, Cruden, etc).
6. Ireland have the best chance to win in NZ (they usually do well over here and hit NZ first up - NZ usally performs at it's worst in the first game of the year).
7. Wales has a realistic chance of beating SA in Wales (most of the SA first team is likely to be rested and Wales have performed well at home).
8. England may really struggle in Australia (NZ). Australia are out to prove a point and are on the up.
9. France could win in SA. That's the French for you. Their team looks on the up and they are the best performing NH team when playing in the SH.
10. Scotland could really struggle in Argentina, especially if the Argentinian 1st team is available.