Saturday 23 April 2011, 11:30
You can read more about her decision to leave the show in an interview in today's Guardian.
Of course the series has not been without its controversy, with some of Anne's remarks at times causing a media storm, not least in Wales.
Like me, Anne's from Liverpool, but that hasn't stopped her aiming a few quips at Scousers and it's that side of her which would be impossible to replace.
Fans of Anne will, of course, continue to be able to see her in Watchdog.
I'm also pleased to announce that Anne will be back in the daytime schedules next year as we have just recommissioned another run of My Life In Books.
In terms of what will replace the Weakest Link, well, that's all still up for debate at the moment.
However, we've been really pleased with how some of our new quizzes on BBC Two have been doing, such as Pointless with Alexander Armstrong. A twittering Stephen Fry has already confirmed himself a keen viewer.
I, for one, am incredibly grateful to Anne in making this quiz such a brilliant watch over the years.
If you'd like to take a trip down memory lane, you can take a look at the very first episode that went out, on the Weakest Link site.
We're planning some special episodes to see the series out, which will be filmed in Glasgow in December 2011, and the show will continue to be on air until Spring 2012.
Liam Keelan is the controller of BBC daytime.
Comments made by writers on the BBC TV blog are their own opinions and not necessarily those of the BBC.
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Tuesday 19 April 2011, 11:24
Sunday 24 April 2011, 10:00