One of the new breed of Irish artists who came into their own in the 1980s, Doyle was born in Dublin. He worked as a schoolteacher for many years in the north Dublin suburb of Kilbarrack, which became the setting for his acclaimed Barrytown trilogy of novels: The Commitments, The Snapper and The Van. Doyle's Kilbarrack/Barrytown describes a bleak modern cityscape that has nothing in common with the literary landscape of Joyce and Yeats, or even of Behan and O'Casey. His characters share a popular urban culture that can be found in many Western cities, although the accent is Irish.The Barrytown trilogy begins with The Commitments, which Doyle published himself in 1987, describing in comic but compassionate terms the lives of a group of Dublin teenagers intent on forming a band. These characters are modelled on boys and girls whom Doyle had taught and are far more influenced by American music and culture than by traditional Irish values. The Commitments was followed by The Snapper in 1990 and The Van in 1991, where the same characters appear. A film version of The Commitments came out in 1991, The Snapper in 1993 and The Van in 1996, with Doyle writing the screenplays for all three.
In 1993, Paddy Clarke Ha Ha Ha was published, winning the Booker Prize and establishing Doyle as a leading comic writer. But underneath the playful and bizarre surface is the sadness that informs all Doyle's work as the 10-year-old narrator watches the estrangement of his parents and their eventual separation. Fatherhood and its failure is a constant theme in Doyle's books, as it is also one of the main themes of 20-century Irish writing.
In 1994, Doyle wrote the script for the BBC series, Family, which depicted domestic violence. This experience provided the stimulus for his novel, The Woman Who Walked Into Doors, (1996). Narrated by a battered wife, this grim account of male brutality caused something of an outcry in Ireland.
In 1999, Doyle moved out of the domestic setting of his previous work with his novel A Star Called Henry, describing scenes from the Irish War of Independence seen through the eyes of Henry Smart, a precocious Dublin street urchin who becomes an IRA assassin.