Woman's Hour will move back to London
The BBC will stop making Woman's Hour in Salford to reduce costs.
The show's production has been split between bases in London and the North West since 2002. One programme a week has been made at MediaCity since 2011, prior to which it was made at BBC Manchester.
Jenni Murray hosts the show three days a week - including the Salford edition - while her counterpart Jane Garvey presents the other two.
But the long-running show will move its production base back to London full time because of a review of Delivering Quality First savings targets.
A BBC spokesperson said: 'As part of BBC Radio's £38m DQF savings target, we have reviewed the way we make programmes and decided that, by having a single production base for Woman's Hour, we can reduce costs without affecting listeners' enjoyment of the programme.'
Last month it was announced that 65 jobs in radio will go as part of a second phase of DQF.
To help find £6m worth of savings, 30 production jobs will be cut, including some producers working at Radios 3 and 4.
The BBC will continue to produce about 3,500 hours of radio from Salford, including Radio 4's You and Yours, which moved to BBC North two years ago. This figure does not include 5 live.